COX-2 Products

Antibodies
COX-2 Antibody
COX-2 Antibody
NB100-689
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P
Host: Rabbit Polyclonal
COX-2 Antibody
COX-2 Antibody
AF4198
Species: Hu, Mu
Applications: WB, CyTOF-ready, ICC, ICFlow
Host: Goat Polyclonal
COX-2 Antibody
COX-2 Antibody
NB110-1948
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
COX-2 Antibody Pair
COX-2 Antibody Pair
H00005743-PW1
Species: Hu
Applications: WB, IP
Lysates
COX-2 Overexpression Lysate ( ...
COX-2 Overexpression Lysate (Denat...
H00005743-T01
Species: Hu
Applications: WB
COX-2 Overexpression Lysate ( ...
COX-2 Overexpression Lysate (Native)
NBP2-10722
Applications: WB
Proteins
Recombinant Human COX-2 Prote ...
Recombinant Human COX-2 Protein
H00005743-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human COX-2 Prote ...
Recombinant Human COX-2 Protein
H00005743-P02
Species: Hu
Applications: WB, ELISA, PA
COX-2 Recombinant Protein Ant ...
COX-2 Recombinant Protein Antigen
NBP1-85499PEP
Species: Hu
Applications: AC
RNAi
COX-2 RNAi
COX-2 RNAi
H00005743-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

COX2 (Cyclooxygenase 2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Rat
Product By Gene ID 5743
Alternate Names
  • PGG/HS
  • EC 1.14.99
  • GRIPGHS
  • Prostaglandin-endoperoxide synthase 2
  • EC 1.14.99.1
  • Cyclooxygenase-2
  • PHS II
  • prostaglandin G/H synthase and cyclooxygenase
  • PGH synthase 2
  • prostaglandin G/H synthase 2
  • PGHS-2
  • hCox-2
  • COX-2
  • cyclooxygenase-2
  • Prostaglandin H2 synthase 2
  • COX2cyclooxygenase 2b
  • PHS-2
  • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase andcyclooxygenase)

Research Areas for COX-2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Biology
Cellular Markers
Cytokine Research
Hypoxia
Lipid and Metabolism
Phospho-Specific
Signal Transduction

Bioinformatics Tool for COX-2

Discover related pathways, diseases and genes to COX-2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related COX-2 Blog Posts

Check out the latest blog posts on COX-2.
SUCNR1/GPR91 - a potential role in renovascular hypertension
SUCNR1 is the cognate receptor for the Kreb's citric acid cycle intermediate succinate. It is of interest to scientists because it is involved in not only energy metabolism but possibly also in renovascular hypertension, a condition linked to diabe...    Read more.
Inhibitor kappa B-alpha (IkappaB-alpha)
The transcription factor nuclear factor kappa beta (NFkB) is highly regulated by triggers such as stress, free-radicals, UV light, and hypoxia. NFkB is one of the fastest responding transcription factors in humans. The NFKB signaling pathway is ess...    Read more.
Read more COX-2 related blogs.