COX-2 Products

Antibodies
COX-2 Antibody
COX-2 Antibody
NB100-689
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
COX-2 Antibody
COX-2 Antibody
NB100-868
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
COX-2 Antibody
COX-2 Antibody
AF4198
Species: Hu, Mu
Applications: WB, CyTOF-ready, Flow, ICC/IF
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human/Mouse Total COX-2 DuoSe ...
Human/Mouse Total COX-2 DuoSet IC ...
DYC4198-2
Species: Hu, Mu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Proteins
Recombinant Human COX-2 His-t ...
Recombinant Human COX-2 His-tag Pr...
10465-CX
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Recombinant Human COX-2 GST ( ...
Recombinant Human COX-2 GST (N-Ter...
H00005743-P02
Species: Hu
Applications: WB, ELISA, PA, AP
COX-2 Recombinant Protein Ant ...
COX-2 Recombinant Protein Antigen
NBP1-85499PEP
Species: Hu
Applications: AC

Description

COX2 (Cyclooxygenase 2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Rat
Product By Gene ID 5743
Alternate Names
  • PGG/HS
  • EC 1.14.99
  • GRIPGHS
  • Prostaglandin-endoperoxide synthase 2
  • EC 1.14.99.1
  • Cyclooxygenase-2
  • PHS II
  • prostaglandin G/H synthase and cyclooxygenase
  • PGH synthase 2
  • prostaglandin G/H synthase 2
  • PGHS-2
  • hCox-2
  • COX-2
  • cyclooxygenase-2
  • Prostaglandin H2 synthase 2
  • COX2cyclooxygenase 2b
  • PHS-2
  • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase andcyclooxygenase)

Research Areas for COX-2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Biology
Cellular Markers
Cytokine Research
Hypoxia
Lipid and Metabolism
Phospho-Specific
Signal Transduction

Bioinformatics Tool for COX-2

Discover related pathways, diseases and genes to COX-2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related COX-2 Blog Posts

Check out the latest blog posts on COX-2.
Increased wild type FUS levels in ALS patients lead to a toxic microenvironment and motor neuron neurodegeneration
By Michalina Hanzel, PhDFUS mutations in Amyotrophic Lateral SclerosisFused in sarcoma (FUS) is a ribonucleoprotein that continuously shuttles between the nucleus and the cytoplasm to regulate pre-mRNA splicing, mRN...    Read more.
SUCNR1/GPR91 - a potential role in renovascular hypertension
SUCNR1 is the cognate receptor for the Kreb's citric acid cycle intermediate succinate. It is of interest to scientists because it is involved in not only energy metabolism but possibly also in renovascular hypertension, a condition linked to diabe...    Read more.
Inhibitor kappa B-alpha (IkappaB-alpha)
The transcription factor nuclear factor kappa beta (NFkB) is highly regulated by triggers such as stress, free-radicals, UV light, and hypoxia. NFkB is one of the fastest responding transcription factors in humans. The NFKB signaling pathway is ess...    Read more.
Read more COX-2 related blogs.