Coronin 3 Antibody (1F7) - Azide and BSA Free

Western Blot: Coronin 3 Antibody (1F7) [H00023603-M02] - CORO1C monoclonal antibody (M02), clone 1F7. Analysis of CORO1C expression in Hela S3 NE.

Immunohistochemistry-Paraffin: Coronin 3 Antibody (1F7) [H00023603-M02] - Analysis of monoclonal antibody to CORO1C on formalin-fixed paraffin-embedded human uterine cervix. Antibody concentration 3 ug/ml.

ELISA: Coronin 3 Antibody (1F7) [H00023603-M02] - Detection limit for recombinant GST tagged CORO1C is 0.1 ng/ml as a capture antibody.

• Reactivity: Hu, Mu, Pm
• Applications: WB, ELISA, IHC
• Clone: 1F7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Coronin 3 Antibody (1F7) - Azide and BSA Free Summary

• Immunogen: CORO1C (NP_055140, 375 a.a. ~ 473 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. EEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIA
• Specificity: CORO1C - coronin, actin binding protein, 1C (1F7)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CORO1C
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Coronin 3 Antibody (1F7) - Azide and BSA Free

• coronin 1C
• coronin, actin binding protein, 1C
• coronin, actin-binding protein, 1C
• coronin-1C
• Coronin-3
• CRNN4
• HCRNN4

Background

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Coronin 3 Antibody (H00023603-M02)(4)

Publications using H00023603-M02

• Jun L, Lusong T, Zongpan J et al. Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis. Cancer Lett. 2021-05-29 [PMID: 34062216]
• Lim JP, Shyamasundar S, Gunaratne J et al. YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro. BMC Cancer 2017-03-16 [PMID: 28302118]
• MA L‚cuyer, O Saint-Laur, L BourbonniŠ, S Larouche, C Larochelle, L Michel, M Charabati, M Abadier, S Zandee, N Haghayegh, E Gowing, C Pittet, R Lyck, B Engelhardt, A Prat Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis Proc. Natl. Acad. Sci. U.S.A, 2017-01-09;114(4):E524-E533. 2017-01-09 [PMID: 28069965]
• Kimura T, Yamaoka M, Taniguchi S et al. Activated Cdc42-Bound IQGAP1 Determines the Cellular Endocytic Site. Mol Cell Biol. 2013-10-07 [PMID: 24100016]

Bioinformatics

• Gene Symbol: CORO1C
• Entrez:
  • 23603(Human)
• Uniprot:
  • NP_055140(Human)