Complement Factor I Antibody (271203) [DyLight 550]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 271203
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 550

Complement Factor I Antibody (271203) [DyLight 550] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Complement Factor I
  Lys19-Val583
  Accession # P05156
• Specificity: Detects human Complement Factor I in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CFI
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Complement Factor I Antibody (271203) [DyLight 550]

• AHUS3
• C3b Inactivator
• C3B/C4B inactivator
• C3BINA
• C3b-inactivator
• CFI
• complement component I
• complement control protein factor I
• complement factor I heavy chain
• Complement Factor I
• EC 3.4.21
• EC 3.4.21.45
• FIC3b-INA
• I factor (complement)
• IF
• KAF
• Konglutinogen-activating factor
• light chain of factor I

Background

Factor I is a plasma protein of molecular weight 88 kDa, consisting of two disulphide linked chains of 50 and 38 kDa. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It has a requirement for protein cofactors for cleavage of these complement proteins, Factor H, CR1 or MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CFI