Complement Component C1rLP Antibody

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Complement Component C1rLP Antibody Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Complement Component C1rLP
  Ser41-Asn487
  Accession # AAI56781
• Specificity: Detects human Complement Component C1rLP in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant mouse C1rLP is observed and less than 5% cross-reactivity with recombinant human (rh) C1R, rhC1S, and rhMASP-3 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: C1RL
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 25 ug/mL
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Complement Component C1rLP Antibody

• C1RL
• C1RL1
• C1RL1complement C1r subcomponent-like protein
• C1r-like protein
• C1r-like serine protease analog protein
• C1r-LPcomplement C1r-like proteinase
• C1RLPEC 3.4.21.-
• CLSPa
• complement component 1, r subcomponent-like
• Complement Component C1rLP
• EC 3.4.21
• EC 3.4.21.41

Background

C1rLP, also known as CLSPa, is a plasma serine protease that is related to the C1r complement component. C1rLP is a 487 amino acid protein that contains one CUB domain and a serine protease domain. C1rLP activates pro-C1s and pro-haptoglobin but also inhibits complement-mediated cytotoxicity. Human and mouse C1rLP share 73% aa sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C1RL
• Uniprot:
  • AAI56781()