Complement Component C1rLP Antibody (393608)

• Reactivity: Hu
• Applications: WB, IP
• Clone: 393608
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

Complement Component C1rLP Antibody (393608) Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Complement Component C1rLP
  Ser41-Asn487
  Accession # AAI56781
• Specificity: Detects human Complement Component C1rLP in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) C1r, rhC1s, rhHaptoglobin, or rhMASP3 is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: C1RL
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Complement Component C1rLP Antibody (393608)

• C1RL
• C1RL1
• C1RL1complement C1r subcomponent-like protein
• C1r-like protein
• C1r-like serine protease analog protein
• C1r-LPcomplement C1r-like proteinase
• C1RLPEC 3.4.21.-
• CLSPa
• complement component 1, r subcomponent-like
• Complement Component C1rLP
• EC 3.4.21
• EC 3.4.21.41

Background

Complement Component 1, r subcomponent-like protein (C1rLP) is a serine protease that is mainly expressed in the liver and has structural similarity to C1r, a component of the classical complement activation pathway. C1rLP activates pro-C1s and pro-haptoglobin. The amino acid sequence of human C1rLP is 99% and 75% identical to that of chimpanzee and dog/mouse/rat, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C1RL
• Uniprot:
  • AAI56781()