Complement C7 Antibody (030-113.7.5.4)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
030-113.7.5.4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Complement C7 Antibody (030-113.7.5.4) Summary

Immunogen
Purified human C7
Specificity
NB100-63270 recognizes complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides. Note that this antibody does not recognise membrane bound complement membrane attack complex. This antibody inhibits lysis of sensitised sheep erythrocytes.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
C7
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
Application Notes
Mouse anti Human C7 antibody, clone 030-113.7.5.4 does not recognize membrane bound complement membrane attack complex. Mouse anti Human C7 antibody, clone 030-113.7.5.4 inhibits lysis of sensitised sheep erythrocytes.
Positive Control
Complement C7 Lysate (NBL1-08541)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Borate buffered saline
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for Complement C7 Antibody (030-113.7.5.4)

  • complement component 7
  • complement component C7

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Complement C7 Antibody (NB100-63270) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol C7
Entrez
Uniprot