COMMD1 Antibody (2A12)

Images

 
Western Blot: COMMD1 Antibody (2A12) [H00150684-M01] - COMMD1 monoclonal antibody (M01), clone 2A12 Analysis of COMMD1 expression in HeLa.
Western Blot: COMMD1 Antibody (2A12) [H00150684-M01] - Analysis of COMMD1 expression in transfected 293T cell line by COMMD1 monoclonal antibody (M01), clone 2A12.Lane 1: COMMD1 transfected lysate(21.2 KDa).Lane 2: ...read more
Immunoprecipitation: COMMD1 Antibody (2A12) [H00150684-M01] - Analysis of COMMD1 transfected lysate using anti-COMMD1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with COMMD1 MaxPab rabbit ...read more
ELISA: COMMD1 Antibody (2A12) [H00150684-M01] - Detection limit for recombinant GST tagged COMMD1 is approximately 0.03ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IP
Clone
2A12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

COMMD1 Antibody (2A12) Summary

Immunogen
COMMD1 (AAH22046, 1 a.a. ~ 191 a.a) full length recombinant protein with GST tag.MAAGELEGGKPLSGLLNALAQDTFHGYPGITEELLRSQLYPEVPPEEFRPFLAKMRGILKSIASADMDFNQLEAFLTAQTKKQGGITSDQAAVISKFWKSHKTKIRESLMNQSRWNSGLRGLSWRVDGKSQSRHSAQIHTPVAIIELELGKYGQESEFLCLEFDEVKVNQILKTLSEVEESISTLISQPN
Specificity
COMMD1 - copper metabolism (Murr1) domain containing 1
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
COMMD1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
  • Immunoprecipitation
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.
Publications
Read Publications using H00150684-M01.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for COMMD1 Antibody (2A12)

  • C2orf5
  • COMM domain-containing protein 1
  • COMMD1
  • copper metabolism (Murr1) domain containing 1
  • copper metabolism gene MURR1
  • MGC27155
  • MURR1
  • MURR1chromosome 2 open reading frame 5 (MURR1)
  • Protein Murr1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for COMMD1 Antibody (H00150684-M01)(10)

We have publications tested in 1 application: WB;IP.


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WB;IP
(1)
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Showing Publications 1 - 10 of 10.
Publications using H00150684-M01 Applications Species
O'Hara A, Simpson J, Morin P et al. P300-mediated acetylation of COMMD1 regulates its stability and the ubiquitination/nucleolar translocation of NF-kB/RelA. J Cell Sci. 2014 Jul 29 [PMID: 25074812]
Schilling D, Bayer C, Li W et al. Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1alpha. PLoS One. 2012 Feb 07 [PMID: 22347438]
Drevillon L, Tanguy G, Hinzpeter A et al. COMMD1-Mediated Ubiquitination Regulates CFTR Trafficking. PLoS One. 2011 Mar 31 [PMID: 21483833]
Vonk WI, Wijmenga C, Berger R et al. Cu/Zn superoxide dismutase maturation and activity are regulated by COMMD1. J Biol Chem. 2010 Jul 1. [PMID: 20595380]
Weiss KH, Lozoya JC, Tuma S et al. Copper-Induced Translocation of the Wilson Disease Protein ATP7B Independent of Murr1/COMMD1 Rab7. Am J Pathol;173(6):1783-1794. 2008 Dec. [PMID: 18974300]
Burkhead JL, Morgan CT, Shinde U et al. COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with PtdIns(4,5)p2. J Biol Chem;284(1):696-707. 2009 Jan 2. [PMID: 18940794]
Maine GN, Mao X, Muller PA et al. COMMD1 expression is controlled by critical residues that determine XIAP binding. Biochem J 2009 Jan 15 [PMID: 18795889] (WB;IP) WB;IP
Huang Y, Wu M, Li HY. Tumor suppressor ARF promotes non-classic proteasomal independent polyubiquitination of COMMD1. J Biol Chem;283(17):11453-60. 2008 Apr 25. [PMID: 18305112]
de Bie P, van de Sluis B, Burstein E et al. Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 reduced stability of ATP7B. Gastroenterology;133(4):1316-26. 2007 Oct. [PMID: 17919502]
Maine GN, Mao X, Komarck CM et al. COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. EMBO J;26(2):436-47. 2007 Jan 24. [PMID: 17183367]

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Bioinformatics

Gene Symbol COMMD1
Entrez
OMIM
Uniprot