Coagulation Factor X Antibody (156106) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 156106
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Coagulation Factor X Antibody (156106) [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Coagulation Factor X
  Leu24-Lys488 (predicted)
  Accession # P00742
• Specificity: Detects human Coagulation Factor X in direct ELISAs and Western blots. It recognizes both Factor X and Factor Xa.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Coagulation Factor X Antibody (156106) [Alexa Fluor® 488]

• Cf10
• Coagulation Factor X
• EC 3.4.21
• EC 3.4.21.6
• F10
• factor Xa
• FX
• FXa
• Prothrombinase
• Stuart Factor
• Stuart-Prower factor

Background

As the only known physiological activator of thrombin, Factor X is a vitamin K-dependent plasma protease that plays a pivotal role in blood coagulation. Human Factor X (rhFX) is initially synthesized in the liver as a single-chain precursor of 488 amino acids (aa) with a signal peptide and a pro region (aa 1‑40). Both the intrinsic and extrinsic pathways activate Factor X to Xa, which consists of light (aa 41‑179) and heavy (aa 235‑488) chains linked by a disulfide bond. The light chain contains a Gla and two EGF-like domains and the heavy chain corresponds to the serine protease domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.