CMTM5 Antibody

Immunohistochemistry-Paraffin: CMTM5 Antibody [NBP2-97355] - Immunochemical staining of human CMTM5 in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.

Product Discontinued

CMTM5 Antibody Summary

• Description: This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with E. coli-derived Human CMTM5 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CMTM5
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 100 mM Tris,100 mM Glycine,10 mM NaCL, pH 8.0
• Preservative: 0.03% Proclin
• Purity: Antigen Affinity-purified

Alternate Names for CMTM5 Antibody

• chemokine-like factor super family 5
• chemokine-like factor superfamily 5
• Chemokine-like factor superfamily member 5
• CKLF-like MARVEL transmembrane domain containing 5
• CKLF-like MARVEL transmembrane domain-containing protein 5
• CKLFSF5
• CMTM 5
• CMTM5
• FLJ37521

Background

CMTM5 (CKLF-like MARVEL transmembrane domain-containing protein 5) has at least six variants from alternative splicing, CMTM5-v1 being the predominant form. Research has revealed this is widely expressed in normal tissues, but commonly silenced or down-regulated in cancer cells as a result of promoter methylation. Studies have found that expression of CMTM5-v1 in tumor cells inhibited proliferation and migration, by inducing apoptosis. Therefore, CMTM5 has tumor suppressor activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CMTM5