CLEC3B/Tetranectin Antibody (5B7) - BSA Free

Western Blot: CLEC3B/Tetranectin Antibody (5B7) - BSA Free [NBP1-05142] - NBP1-05142 used in SDS-PAGE 12%. Tertanectin band is visable at 22kDa. Lane1: MWM. Lane 2: human serum (20 uL 1:50). Lane 3 Bovine serum (20uL 1:10). Image courtesy of Isabelle Naegelen, University of Luxemburg

Immunocytochemistry/Immunofluorescence: CLEC3B/Tetranectin Antibody (5B7) - BSA Free [NBP1-05142] - For confocal microscopy, NBP1-05142 used to stain human neutrophils A) DAPI-stained, B) tetranectin-stained, and C) overlay picture . Image courtesy of Isabelle Naegelen, University of Luxemburg

Product Discontinued

CLEC3B/Tetranectin Antibody (5B7) - BSA Free Summary

• Immunogen: Tetranectin purified from human citrate plasma (3) and coupled to PPD. Boosted before fusion with recombinant tetranectin produced in E. coli.
• Specificity: Specific for amino acids 17-181 of human tetranectin monomer
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CLEC3B
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:25
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:40
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for CLEC3B/Tetranectin Antibody (5B7) - BSA Free

• CLEC3B
• C-type lectin domain family 3 member B
• C-type lectin domain family 3, member B
• DKFZp686H17246
• Plasminogen kringle 4-binding protein
• TETN
• tetranectin (plasminogen binding protein)
• Tetranectin
• TNA
• TNAtetranectin (plasminogen-binding protein)
• TNtetranectin

Background

Tetranectin (TN) is a serum and tissue protein, a C-type lectin, which binds to Ca++. It is a homotrimer of monomers each with a mass of 20 kDa, plasma or serum concentrations of TN are found to be approximately 10 mg/l (1,2,4). In vitro, TN can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine (3). TN is best known as a prognostic marker in ovarian cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CLEC3B