Recombinant Human CLCN3 GST (N-Term) Protein

Recombinant Human CLCN3 Protein [H00001182-Q01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

• Reactivity: Hu
• Applications: WB, ELISA, MA, AP

Recombinant Human CLCN3 GST (N-Term) Protein Summary

• Description: A recombinant protein with a N-terminal GST tag corresponding to the amino acid sequence 1-99 of Human CLCN3
  
  

  Source: Wheat Germ (in vitro)

  Amino Acid Sequence: MESEQLFHRGYYRNSYNSITSASSDEELLDGAGVIMDFQTSEDDNLLDGDTAVGTHYTMTNGGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKCK

• Preparation Method: in vitro wheat germ expression system
• Details of Functionality: This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
• Source: Wheat germ
• Protein/Peptide Type: Recombinant Protein
• Gene: CLCN3
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoaffinity Purification
  • Protein Array
  • Western Blot
• Theoretical MW: 36.63 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human CLCN3 GST (N-Term) Protein

• chloride channel 3
• Chloride channel protein 3
• Chloride transporter ClC-3
• CLC3
• ClC-3
• H(+)/Cl(-) exchange transporter 3

Background

CLCN3 mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to theacidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis.May play an important role in n

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for CLCN3 Partial Recombinant Protein (H00001182-Q01)(1)

Publication using H00001182-Q01

• McGonigle S, Majumder U, Kolber-Simonds D et al. Neuropilin-1 drives tumor-specific uptake of chlorotoxin Cell Commun. Signal 2019-06-17 [PMID: 31208428] (WB)

Bioinformatics

• Gene Symbol: CLCN3