Citidine Deaminase Antibody

Product Discontinued

Citidine Deaminase Antibody Summary

• Immunogen: Purified yeast cytosine deaminase
• Specificity: This is specific for cytosine deaminase. It recognises the native antigen in ELISA, and in Western blot two bands were visualised by ECL at 13kD and 17kD.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: CDA
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:500-1:2500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:100-1:500

Reactivity Notes

Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 5.0 mg/ml
• Purity: Protein G purified

Alternate Names for Citidine Deaminase Antibody

• CDA
• CDD
• CDDCytidine aminohydrolase
• Citidine Deaminase
• cytidine deaminase
• cytosine nucleoside deaminase
• EC 3.5.4.5
• small cytidine deaminase

Background

Cytosine deaminase belongs to the cytidine and deoxycytidylate deaminase family. This enzyme converts cytosine to uracil or 5-methylcytosine to thymine by deaminating carbon number 4. It is present in prokaryotes and fungi but not in multicellular eukaryotes and is an important member of the pyrimidine salvage pathway. The enzyme is of widespread interest both for antimicrobial drug design and for gene therapy applications against tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Citidine Deaminase Antibody (NB100-66413)(1)

Publication using NB100-66413

• Yu, S-T, Li, C, Lu, M-H et al. Noninvasive and real-time monitoring of the therapeutic response of tumors in vivo with an optimized hTERT promoter Cancer 2012-01-01 [PMID: 22009660] (IF/IHC, WB, Human)

Bioinformatics

• Gene Symbol: CDA
• Uniprot:
  • Q12178(Yeast)