CIN85/SH3KBP1 Antibody (931308) [FITC]

• Reactivity: Hu
• Applications: WB
• Clone: 931308
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

CIN85/SH3KBP1 Antibody (931308) [FITC] Summary

• Immunogen: E. coli-derived recombinant human CIN85/SH3KBP1
  Pro366-Lys665
  Accession # Q96B97
• Specificity: Detects human CIN85/SH3KBP1 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SH3KBP1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for CIN85/SH3KBP1 Antibody (931308) [FITC]

• C-Cbl-Interacting Protein
• CD2-binding protein 3
• CD2BP3
• CIN85
• CIN85Cbl-interacting protein of 85 kDa
• GIG10
• HSB1
• HSB-1
• Human Src family kinase-binding protein 1
• MIG18
• migration-inducing gene 18
• SH3 domain-containing kinase-binding protein 1
• SH3-domain kinase binding protein 1
• SH3KBP1
• Src family kinase-binding protein 1
• src-related kinase binding protein-1

Background

CBL (MIM 165360) constitutively interacts with SH3 domain-containing proteins and, upon tyrosine phosphorylation, with SH2 domain-containing proteins. The SH3KBP1 gene encodes an 85-kD CBL-interacting protein that enhances tumor necrosis factor (MIM 191160)-mediated apoptotic cell death (Narita et al., 2001 [PubMed 11474197]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SH3KBP1