cIAP-2/HIAP-1 Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

cIAP-2/HIAP-1 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-BIRC3 full-length
Gene
BIRC3

Applications/Dilutions

Publications
Read Publication using H00000330-T01.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for cIAP-2/HIAP-1

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-BIRC3 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for cIAP-2/HIAP-1 Overexpression Lysate (Denatured)

  • AIP1
  • API2
  • BIRC3 baculoviral IAP repeat containing 3
  • BIRC3
  • cIAP2
  • c-IAP2
  • cIAP-2
  • HAIP1
  • HIAP1
  • HIAP-1
  • MALT2
  • MIHC
  • RNF49

Background

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq]. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Applications: WB

Publications for cIAP-2/HIAP-1 Lysate (H00000330-T01)(1)

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Blogs on cIAP-2/HIAP-1.

cIAP2 - balancing cell death and cell survival
The inhibitor of apoptosis proteins (IAPs) are important regulators of cell death and inflammation. The cellular inhibitor of apoptosis protein 2 (cIAP2) contains three Baculovirus IAP repeat (BIR) domains, a Ubiquitin associated (UBA) domain, and...  Read full blog post.

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Bioinformatics

Gene Symbol BIRC3
Entrez