Chymotrypsin C/CTRC Antibody (CHYMO10-104.5 (4E1))

Immunohistochemistry-Paraffin: Chymotrypsin C/CTRC Antibody (4E1) [NBP1-72014] - Analysis of anti-Chymotrypsin antibody with human pancreas at concentration 5 ug/ml.

Product Discontinued

Chymotrypsin C/CTRC Antibody (CHYMO10-104.5 (4E1)) Summary

• Immunogen: Purified human pancreatic chymotrypsin.
• Specificity: Human chymotrypsin-C, also known as chymotrypsin or caldecrin. Chymotrypsin is a 239 amino acid ~30 kD protease with an additional 13 amino acid propeptide region and a 16 amino acid signal peptide. Variations in the CTRC gene has been associated with susceptibility to hereditary, pancreatitis, a disease characterized by pancreatic inflammation and destruction of the parenchyma.
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Gene: CTRC
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen 1:10 - 1:500
  • Immunohistochemistry-Paraffin 5 - 10 ug/ml
  • Western Blot 1:100 - 1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Chymotrypsin C/CTRC Antibody (CHYMO10-104.5 (4E1))

• Caldecrin
• chymotrypsin C (caldecrin)
• Chymotrypsin C
• chymotrypsin-C
• CLCR
• CLCRserum calcium decreasing factor
• CTRC
• EC 3.4.21
• EC 3.4.21.2
• ELA4
• elastase 4
• Elastase IV

Background

The Chymotrypsin C gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has no

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for Chymotrypsin C/CTRC Antibody (NBP1-72014). (Showing 1 - 2 of 2 FAQ).

1. Can you tell me Chymotrypsin C Antibody (NBP1-72014) use for rat IHC-P?
   • This antibody has been validated for use in rat in IHC-P with a recommended dilution of 5 - 10 ug/ml.
2. Does Chymotrypsin C Antibody (4E1), cat# NBP1-72014 recognize CTRC in C56Bl/6 mice?
   • All of our primary antibodies are guaranteed to work in the species and applications listed on the product datasheet and on the website. Our Chymotrypsin C antibody with catalog number NBP1-72014 is covered by the Novus Guarantee to detect the protein in human, mouse and rat samples by Western blotting, ELISA and IHC . If you are using one of these applications then the antibody should be suitable for your requirements. If a Novus product fails to meet the criteria stated on the product datasheet, our technical service team will work with you to troubleshoot the issue. If this process is not successful, Novus will provide you with a free replacement or a 100% refund for the product.

Bioinformatics

• Gene Symbol: CTRC