Chromogranin B Antibody (CL11393) - BSA Free

Staining of human Liver shows no positivity in hepatocytes as expected.

Staining of human Cerebral cortex shows strong cytoplasmic positivity in neuropil.

Staining of human Adrenal gland shows strong cytoplasmic positivity in neuroendocrine cells.

Analysis in human adrenal gland and liver tissues using NBP3-21192 antibody. Corresponding CHGB RNA-seq data are presented for the same tissues.

Staining of human Pancreas shows moderate cytoplasmic positivity in islets of Langerhans.

Staining of human Small intestine shows strong cytoplasmic positivity in enteroendocrine cells.

• Reactivity: Hu
• Applications: IHC
• Clone: CL11393
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Chromogranin B Antibody (CL11393) - BSA Free Summary

• Description: Novus Biologicals Mouse Chromogranin B Antibody (CL11393) - BSA Free (NBP3-21192) is a monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed using a recombinant protein derived from P05060, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CHGB
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000- 1:2500
  • Immunohistochemistry-Paraffin 1:1000- 1:2500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for Chromogranin B Antibody (CL11393) - BSA Free

• CgB
• CHGB
• chromogranin B (secretogranin 1)
• Chromogranin B
• Chromogranin-B
• SCG1
• SCG1sgI
• secretogranin B
• Secretogranin I
• secretogranin-1
• SgI

Background

The Chromogranin B gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. Thisprotein may serve as a precursor for regulatory peptides. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CHGB