CHD5 Recombinant Enzymes

• Reactivity: Hu
• Applications: NULL

CHD5 Recombinant Enzymes Summary

• Description: Human CHD5 (aa 3-1954) fused to 6xHis and FLAG-tag at the N-terminus. (Uniprot: Q8TDI0)
• Source: Sf 9 (baculovirus)
• Protein/Peptide Type: Recombinant Enzymes
• Gene: CHD5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • N/A

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl, pH 7.9, 150 mM NaCl, 15% glycerol, 2 mM MgCl2, 0.2 mM EDTA, 1 mM DTT, 10 mM beta-glycerophospate, 0.4 mM PMSF, 1 mM benzamidine and 0.4 mg/ml recombinant human insulin
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for CHD5 Recombinant Enzymes

• ATP-dependent helicase CHD5
• CHD-5
• chromodomain helicase DNA binding protein 5
• chromodomain-helicase-DNA-binding protein 5
• DKFZp434N231
• EC 3.6.1
• EC 3.6.4.12
• KIAA0444

Background

Changes in gene expression are associated with changes in chromatin structure, which can result from modification of histones by acetylation and methylation. In addition, SWI/SNF proteins can effect chromatin structure and gene expression by causing ATP-dependent disruption of the nucleosome and by enhancing binding of transcription factors. CHD5 belongs to a group of SWI/SNF proteins called CHD proteins, which contain a SWI/SNF-like helicase/ATPase domain, as well as a DNA-binding domain and a chromodomain that directly modifies chromatin structure (Thompson et al., 2003 (PubMed 12592387)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CHD5