CHD5 Products

Description

Changes in gene expression are associated with changes in chromatin structure, which can result from modification of histones by acetylation and methylation. In addition, SWI/SNF proteins can effect chromatin structure and gene expression by causing ATP-dependent disruption of the nucleosome and by enhancing binding of transcription factors. CHD5 belongs to a group of SWI/SNF proteins called CHD proteins, which contain a SWI/SNF-like helicase/ATPase domain, as well as a DNA-binding domain and a chromodomain that directly modifies chromatin structure (Thompson et al., 2003 (PubMed 12592387)).(supplied by OMIM)

Bioinformatics

Uniprot	Q8TDI0 Human
Product By Gene ID	26038
Alternate Names	ATP-dependent helicase CHD5 CHD-5 chromodomain helicase DNA binding protein 5 chromodomain-helicase-DNA-binding protein 5 DKFZp434N231 EC 3.6.1 EC 3.6.4.12 KIAA0444

Research Areas for CHD5

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Chromatin Modifiers