CDCP1 Antibody (309116) [Alexa Fluor® 647]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
309116
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 647
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

CDCP1 Antibody (309116) [Alexa Fluor® 647] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human CDCP1
Ala33-Leu666
Accession # NP_073753
Specificity
Detects human CDCP1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse CDCP1 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CDCP1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CDCP1 Antibody (309116) [Alexa Fluor® 647]

  • CD318 antigen
  • CD318
  • CDCP1
  • CUB domain containing protein 1
  • CUB domain-containing protein 1
  • Membrane glycoprotein gp140
  • SIMA135
  • SIMA135TRASK
  • Subtractive immunization M plus HEp3-associated 135 kDa protein
  • Transmembrane and associated with src kinases

Background

CDCP1, also known as SIMA135, is a novel 140 kDa type I transmembrane glycoprotein with three CUB protein-protein interaction domains in its 635 aa extracellular region. The 148 aa cytoplasmic region contains canonical phosphorylation sites for Sre kinase family members and binding sites for SH3 domains. By alternative splicing, a secreted 310 aa residue form of CDCP1 also exists. The amino-terminal region of approximately 265 aa of the type I membrane CDCP1 can also be proteolytically cleaved. CDCP1 is found on the surface of epithelial and bone marrow-derived stem cells. The extracellular region of human CDCP1 shares 84% aa identity with that of the mouse protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for CDCP1 Antibody (FAB26663R) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB26663U
Alexa Fluor 405 FAB26663V
Alexa Fluor 488 FAB26663G
Alexa Fluor 594 FAB26663T
Alexa Fluor 647 FAB26663R
Alexa Fluor 700 FAB26663N
Alexa Fluor 750 FAB26663S

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Bioinformatics

Gene Symbol CDCP1
Uniprot