CDC73/HRPT2 Antibody

Images

 
Western Blot: HRPT2 Antibody [NB200-185] - Detection of Human Parafibromin on HeLa whole cell lysate using NB200-185. In B, Parafibromin was immunoprecipitated by using NB200-185 or control rabbit IgG.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB200-185
    • Availability
      Product Discontinued

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CDC73/HRPT2 Antibody Summary

Immunogen
A synthetic peptide which maps to a region between residues 375 and 425 of human Parafibromin using the numbering given in TrEMBL entry Q6P1J9 (GeneID 79577).
Specificity
NB200-185 is specific for human Parafibromin protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CDC73
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:10000-1:30000
  • Immunoprecipitation 1-4 ug/mg lysate
Application Notes
Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use.
Positive Control
CDC73/HRPT2 Lysate (NBL1-09015)
Publications
Read Publication using NB200-185.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CDC73/HRPT2 Antibody

  • C1orf28hyperparathyroidism 2 (with jaw tumor)
  • CDC73
  • cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S.cerevisiae)
  • Cell division cycle protein 73 homolog
  • chromosome 1 open reading frame 28
  • HPTJT
  • HPT-JT
  • HRPT2
  • HRPT2FLJ23316
  • Hyperparathyroidism 2 protein
  • HYX
  • Parafibromin

Background

Parafibromin, the product of gene HPRT2, acts as a tumor suppressor protein by inhibiting cell proliferation and blocking expression of cyclin D1 when overexpressed. Parafibromin has also been shown to bind with the PAF1 complex / RNA polymerase II which is involved with transcription elongation and the RNA processing pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CDC73/HRPT2 Antibody (NB200-185)(1)

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol CDC73
Entrez
Uniprot