CDC73/HRPT2 Antibody [DyLight 594]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 594

CDC73/HRPT2 Antibody [DyLight 594] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residues 250 and 300 of human Parafibromin using the numbering given in TrEMBL entry Q6P1J9 (GeneID 79577).
• Specificity: NB200-184 is specific for human Parafibromin protein.
• Predicted Species: Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDC73
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CDC73/HRPT2 Antibody [DyLight 594]

• C1orf28hyperparathyroidism 2 (with jaw tumor)
• CDC73
• cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S.cerevisiae)
• Cell division cycle protein 73 homolog
• chromosome 1 open reading frame 28
• HPTJT
• HPT-JT
• HRPT2
• HRPT2FLJ23316
• Hyperparathyroidism 2 protein
• HYX
• Parafibromin

Background

Parafibromin, the product of gene HPRT2, acts as a tumor suppressor protein by inhibiting cell proliferation and blocking expression of cyclin D1 when overexpressed. Parafibromin has also been shown to bind with the PAF1 complex / RNA polymerase II which is involved with transcription elongation and the RNA processing pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC73