CDC42EP1 Antibody (SD08-54)

Western Blot: CDC42EP1 Antibody (SD08-54) [NBP2-67829] - Analysis of CDC42EP1 on different lysates using anti-CDC42EP1 antibody at 1/1,000 dilution. Positive control: Lane 1: HUVEC Lane 2: Hela

Product Discontinued

CDC42EP1 Antibody (SD08-54) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic peptide within Human CDC42EP1 aa 310-359 / 391. (SwissProt: Q00587 Human)
• Localization: Endomembrane system, Cytoplasm.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: CDC42EP1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for CDC42EP1 Antibody (SD08-54)

• Binder of Rho GTPases 5
• Borg5
• BORG5cdc42 effector protein 1
• CDC42 effector protein (Rho GTPase binding) 1
• CEP155 kDa bone marrow stromal/endothelial cell protein
• MSE55MGC15316
• serum constituent protein
• Serum protein MSE55

Background

CDC42EP1, also known as CDC42 Effector Protein 1, consists of a 40.2 kDa and 39.7 kDa isoform, and is involved in regulatory processes within the cell as a member of the Rho GTPase family. Most commonly found in bone marrow, the CDC42EP1 proteins been shown to help facilitate actin cytoskeleton restructuring and cell shape regulation. The protein is being studied for its involvement in osteonecrosis. The protein has been linked to the RhoA and Rho GTPases pathways where it interacts with MAPKAP1, RPTOR, RHOQ, CDC42, RBPMS, KRTAP4-12, PLSCR1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC42EP1