CD39L2/ENTPD6 Antibody (494402)

• Reactivity: Hu
• Applications: WB, IP
• Clone: 494402
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

CD39L2/ENTPD6 Antibody (494402) Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human CD39L2/ENTPD6
  Lys61-Ser484
  Accession # O75354
• Specificity: Detects human CD39L2/ENTPD6 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) CD39, rhCD39L3, or recombinant mouse CD39 is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: ENTPD6
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD39L2/ENTPD6 Antibody (494402)

• CD39 antigen-like 2
• CD39L2
• CD39L2NTPDase-6
• CD39-like 2
• dJ738P15.3
• DKFZp781G2277
• DKFZp781K21102
• EC 3.6.1.6
• ectonucleoside triphosphate diphosphohydrolase 6 (putative function)
• ectonucleoside triphosphate diphosphohydrolase 6 (putative)
• ectonucleoside triphosphate diphosphohydrolase 6
• ENTPD6
• FLJ36711
• IL-6SAG
• IL6ST2
• interleukin 6 signal transducer-2
• NTPD3
• NTPDase 6

Background

ENTPD6 (ectonucleoside triphosphate diphosphohydrolase-6), also known as CD39L2, is a secreted nucleoside phosphohydrolase, which catalyzes the hydrolysis of extracellular nucleotides, such as nucleoside 5'-diphosphates and nucleoside 5'-triphosphates (1). Human ENTPD6 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). It has a broad tissue distribution, with major expression in the heart. The amino acid sequence of human CD39L2 shares 99%, 88% and 87% identity with that of chimpanzee, mouse and dog, respectively.

1. Chadwick, B.P. and A.M. Frischauf (1998) Genomics. 50:357.
2. Hicks-Berger, C.A. et al. (2000) J. Biol. Chem. 275:34041.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ENTPD6
• Uniprot:
  • O75354()