CD39L2/ENTPD6 Antibody (494402) [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Clone: 494402
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

CD39L2/ENTPD6 Antibody (494402) [Alexa Fluor™ Plus 488] Summary

• Specificity: Detects human CD39L2/ENTPD6 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) CD39, rhCD39L3, or recombinant mouse CD39 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD39L2/ENTPD6 Antibody (494402) [Alexa Fluor™ Plus 488]

• CD39 antigen-like 2
• CD39L2
• CD39L2NTPDase-6
• CD39-like 2
• dJ738P15.3
• DKFZp781G2277
• DKFZp781K21102
• EC 3.6.1.6
• ectonucleoside triphosphate diphosphohydrolase 6 (putative function)
• ectonucleoside triphosphate diphosphohydrolase 6 (putative)
• ectonucleoside triphosphate diphosphohydrolase 6
• ENTPD6
• FLJ36711
• IL-6SAG
• IL6ST2
• interleukin 6 signal transducer-2
• NTPD3
• NTPDase 6

Background

ENTPD6 (ectonucleoside triphosphate diphosphohydrolase-6), also known as CD39L2, is a secreted nucleoside phosphohydrolase, which catalyzes the hydrolysis of extracellular nucleotides, such as nucleoside 5'-diphosphates and nucleoside 5'-triphosphates (1). Human ENTPD6 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). It has a broad tissue distribution, with major expression in the heart. The amino acid sequence of human CD39L2 shares 99%, 88% and 87% identity with that of chimpanzee, mouse and dog, respectively.

1. Chadwick, B.P. and A.M. Frischauf (1998) Genomics. 50:357.
2. Hicks-Berger, C.A. et al. (2000) J. Biol. Chem. 275:34041.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.