CD39L2/ENTPD6 Products

Description

CD39L2, also known as ectonucleoside triphosphate diphosphohydrolase-6 (ENTPD-6) and NTPDase-6, is a nucleoside phosphohydrolase of the CD39 family of enzymes that is present on the surface of cells (1). This Type II membrane protein also exists as a soluble, secreted protein. CD39L2 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). Nucleoside-5’-triphosphates are also hydrolyzed, but at much lower rates. CD39L2 is expressed at its highest levels in cardiac muscle and in heart capillary endothelial cells (3). CD39L2 may play a functional role in the regulation and recruitment of platelet activation in the heart. The cytoplasmic and transmembrane domains of rmCD39L2 were replaced with a signal sequence, resulting in the secretion of the recombinant protein.

Bioinformatics

Uniprot	742115
Product By Gene ID	955
Alternate Names	CD39 antigen-like 2 CD39L2 CD39L2NTPDase-6 CD39-like 2 dJ738P15.3 DKFZp781G2277 DKFZp781K21102 EC 3.6.1.6 ectonucleoside triphosphate diphosphohydrolase 6 (putative function) ectonucleoside triphosphate diphosphohydrolase 6 (putative) ectonucleoside triphosphate diphosphohydrolase 6 ENTPD6 FLJ36711 IL-6SAG IL6ST2 interleukin 6 signal transducer-2 NTPD3 NTPDase 6