CD302/CLEC13A Antibody (662714) [Alexa Fluor® 532]

• Reactivity: Mu
• Applications: WB
• Clone: 662714
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 532

CD302/CLEC13A Antibody (662714) [Alexa Fluor® 532] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse CD302/CLEC13A
  Met1-Cys165
  Accession # Q9DCG2
• Specificity: Detects mouse CD302/CLEC13A in direct ELISAs and Western blots. In direct ELISAs, less than 25% cross-reactivity with recombinant human (rh) CD302 is observed. No cross-reactivity with rhCLEC1, 2, 2A, 3B, 9A, 10A, 12B, 14A, recombinant mouse CLEC4B2, 9A,
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD302/CLEC13A Antibody (662714) [Alexa Fluor® 532]

• BIMLEC
• CD302 antigenC-type lectin domain family 13, member A
• CD302 molecule
• CD302
• CLEC13A
• CLEC13AMGC22301
• C-type lectin domain family 13 member A
• DCL1
• DCL-1
• DCL1C-type lectin BIMLEC
• KIAA0022FLJ43091
• Type I transmembrane C-type lectin receptor DCL-1

Background

CD302, also known as CLEC13A and DCL-1, is a 35 kDa type I transmembrane glycoprotein in the C-type lectin family. CD302 is expressed on monocytes, macrophages, dendritic cells, and granulocytes. It contains one carbohydrate binding domain in its extracellular region and can mediate antigen uptake. In human Hodgkin’s disease, a fusion protein containing portions of CD302 and the ECD of DEC-205 is expressed on Reed-Sternberg cells.  Within the ECD, mouse CD302 shares 82% and 92% aa sequence identity with human and rat CD302, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.