CD23/Fc epsilon RII Antibody Pair

Product Discontinued

CD23/Fc epsilon RII Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: mouse monoclonal anti-FCER2 (300 ul)
• Antibody pair for WB: rabbit polyclonal anti-FCER2 (50 ul)
• Clonality: Polyclonal
• Gene: FCER2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CD23/Fc epsilon RII Antibody Pair

• BLAST-2
• CD23
• CD23A
• CD23CD23 antigen
• CLEC4J
• CLEC4JC-type lectin domain family 4 member J
• C-type lectin domain family 4, member J
• Fc epsilon RII
• Fc fragment of IgE, low affinity II, receptor for (CD23)
• FCE2Fc fragment of IgE, low affinity II, receptor for (CD23A)
• fc-epsilon-RII
• FCER2
• Fcer2a
• FceRII
• IGEBF
• Immunoglobulin E-binding factor
• low affinity immunoglobulin epsilon Fc receptor
• Ly-42
• Lymphocyte IgE receptor

Background

The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: FCER2