CBX1 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

CBX1 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human CBX1
  
  

  Source: E.coli

  Amino Acid Sequence: ERLTWHSYPSEDDDKKDDKN

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: CBX1
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10-100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP3-24706It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for CBX1 Recombinant Protein Antigen

• CBXM31HP1-BETA
• chromobox homolog 1 (Drosophila HP1 beta)
• chromobox homolog 1 (HP1 beta homolog Drosophila )
• chromobox homolog 1
• chromobox protein homolog 1
• Heterochromatin protein 1 homolog beta
• heterochromatin protein 1-beta
• heterochromatin protein p25 beta
• Heterochromatin protein p25
• HP1 beta homolog
• HP1 beta
• HP1Hsbeta
• HP1Hs-beta
• MOD1
• Modifier 1 protein
• p25beta

Background

HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CBX1