Caveolin-3 Antibody (SY22-06)

Western Blot: Caveolin-3 Antibody (SY22-06) [NBP2-67424] - Analysis of Caveolin-3 on different lysates using anti-Caveolin-3 antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse heart Lane 2: Mouse skeletal muscle

Product Discontinued

Caveolin-3 Antibody (SY22-06) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Recombinant protein within Human Caveolin-3 aa 1-125 / 151. (SwissProt: P56539 Human; SwissProt: P51637 Mouse; SwissProt: P51638 Rat)
• Localization: Golgi apparatus membrane, Cell membrane, Membrane.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: CAV3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot 1:1000-1:5000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Caveolin-3 Antibody (SY22-06)

• CAV3
• caveolin 3
• Caveolin3
• Caveolin-3
• LGMD1C
• LGMD1CMGC126100
• LQT9
• LQT9MGC126101
• M-caveolin
• MGC126129
• VIP21
• VIP-21

Background

Caveolin 3 encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CAV3