Cathepsin B Native Protein

Product Discontinued

Cathepsin B Native Protein Summary

• Description: Native Cathepsin B
  
  Source:Human liver
  Amino Acid Sequence:(P07858)
  
  This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab62271)
• Source: Human liver
• Protein/Peptide Type: Native Protein
• Gene: CTSB
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Application Notes: Unit Definition: >200 units/mg protein. One unit is defined as the amount of enzyme that hydrolyzes one nmol Z-Arg-Arg-AFC substrate per minute at 37C pH 6.0 with 10 mM DTT.
  Specific activity: 470 units/mg

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 50 mM sodium acetate (pH 5.0), 1 mM EDTA
• Concentration: 1 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Cathepsin B Native Protein

• APP secretase
• APPS
• Cathepsin B
• Cathepsin B1
• CPSBamyloid precursor protein secretase
• CTSB
• cysteine protease
• EC 3.4.22
• EC 3.4.22.1

Background

Cathepsin B is a lysosomal cysteine protease. It is implicated in playing a role in protein degradation, arthritis, apoptosis, and cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for Cathepsin B Native Protein (NBP1-99197)(1)

Publication using NBP1-99197

• Sesma JI, Wu B, Stuhlmiller TJ, Scott DW. SPX-101 is stable in and retains function after exposure to cystic fibrosis sputum J. Cyst. Fibros. 2018-06-20 [PMID: 29936069] (Human)

Bioinformatics

• Gene Symbol: CTSB