Cathepsin B Antibody


Western Blot: Cathepsin B Antibody [NBP1-19797] - extracts from COLO cells.
Immunocytochemistry/ Immunofluorescence: Cathepsin B Antibody [NBP1-19797] - ICC/IF analysis of HeLa cells using 1:50 dilution of Cathepsin B antibody followed by detection using Dylight 488 labelled secondary antibody more
Immunohistochemistry-Paraffin: Cathepsin B Antibody [NBP1-19797] - Human brain tissue.
Immunohistochemistry-Paraffin: Cathepsin B Antibody [NBP1-19797] - Staining for Cathepsin B in mouse ureter.

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
1.0 mg/ml

Order Details

Cathepsin B Antibody Summary

Synthetic peptide made to an internal portion of the Cathepsin B human protein (between residues 200-270) [UniProt P07858]
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified


Read Publication using
NBP1-19797 in the following applications:

  • WB
    1 publication

Reactivity Notes

Immunogen has 84% homology to bovine and chicken.

Alternate Names for Cathepsin B Antibody

  • APP secretase
  • APPS
  • cathepsin B
  • Cathepsin B1
  • CPSBamyloid precursor protein secretase
  • CTSB
  • cysteine protease
  • EC 3.4.22
  • EC


The cathepsin protease family contains several diverse classes of enzymes. Cathepsins B, L, H, K, S and O are part of the cysteine protease class. Cathepsin B is a dimer consisting of a heavy chain and a light chain cross-linked by a disulfide bond and is a lysosomal cysteine protease. Cathepsin B is expressed in luminal epithelial cells and its expression indicates that Cathepsin B is a marker for secretory cell death. Cathepsin B also participates in intracellular degradation and turnover of proteins.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, IHC-FrFl
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Applications: WB, IHC, IHC-P

Publications for Cathepsin B Antibody (NBP1-19797)(1)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: WB.

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Showing Publication 1 - 1 of 1.
Publication using NBP1-19797 Applications Species
Farizatto K. Study of hyperphosphorylated Tau protein degradation by proteasome-independent pathways, in an experimental model of neurodegeneration Thesis. 2014 Apr 28 (WB, Rat) WB Rat

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Product General Protocols

View specific protocols for Cathepsin B Antibody (NBP1-19797): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

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Blogs on Cathepsin B.

Cathepsin B - a lysosomal protease with potential of an important drug target in neurological diseases and cancer
Cathepsins are a family of lysosomal proteases (serine, aspartic and cysteine proteases) that acts in conjunction with lipases and nucleases to degrade biological macromolecules in the lysosomes (1). While most cathepsins are ubiquitously expressed...  Read full blog post.

Caspase 11: A novel non-canonical inflammasomes
Cell death via apoptosis is a key cellular function triggered by the cell death receptor family and their ligands. This regulated process then transmits downstream signals through adaptor molecules ending with the caspase cysteine proteases. Caspas...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol CTSB

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