Caspase-11 Antibody (8A5) [PerCP]

• Reactivity: Mu, Rt
• Applications: WB, ELISA, Flow, IP
• Clone: 8A5
• Clonality: Monoclonal
• Host: Rat
• Conjugate: PerCP

Caspase-11 Antibody (8A5) [PerCP] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Recombinant mouse caspase-11 (p20 fragment).
• Specificity: Recognizes mouse and rat full-length caspase-11 protein. Detects two bands of ~38kDa and ~43kDa by Western blot.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Rat
• Gene: Casp4
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-80099. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for Caspase-11 Antibody (8A5) [PerCP]

• ich-3
• CASP11
• CASP-11
• CASP4
• CASP-4
• caspase 4, apoptosis-related cysteine peptidase
• Caspl

Background

Caspase-11 (also known as CASP11, CASP4, and ich-3) is one of several different types of caspases. The general role of caspases is to assist in cell death as well as inflammation. More specifically, caspase-11 is involved with pyroptotic cell death. Its structure is heterotrimeric, consisting of two antiparallel heterodimers. Novus offers Caspase 11 antibodies, Peptides and Proteins, Lysates, and RNAi.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: Casp4