Carboxylesterase 2/CES2 Antibody (861429) [Janelia Fluor® 525]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clone: 861429
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 525

Carboxylesterase 2/CES2 Antibody (861429) [Janelia Fluor® 525] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Carboxylesterase 2/CES2
  Gln27-Leu559
  Accession # O00748
• Specificity: Detects human Carboxylesterase/CES2 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Carboxylesterase 2/CES2 Antibody (861429) [Janelia Fluor® 525]

• carboxylesterase 2 (intestine, liver)
• Carboxylesterase 2
• carboxylesterase 2EC 3.1.1.1
• CE-2
• CE-2PCE-2
• CES2
• CES2A1
• EC 3.1.1
• EC 3.1.1.84
• hCE-2
• iCE
• intestinal carboxylesterase; liver carboxylesterase-2
• PCE-2

Background

Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.