Carbonic Anhydrase X/CA10 Antibody (862319) [Alexa Fluor® 350]

• Applications: WB
• Clone: 862319
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

Carbonic Anhydrase X/CA10 Antibody (862319) [Alexa Fluor® 350] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Carbonic Anhydrase X/CA10
  Met1-Asn300
  Accession # Q9NS85
• Specificity: Detects human Carbonic Anhydrase X/CA10 in ELISAs and Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

CA10 (Carbonic Anhydrase-related X), also called CARP X and Cerebral protein 15, is a cytosolic 35 kDa (predicted) member of the a-carbonic anhydrase family of molecules. Although it does not possess CA enzymatic activity due to the lack of Zn and His in its (potential) catalytic site, the recombinant protein used as an immunogen does show esterase activity. CA10 is found principally in CNS neurons and respiratory epithelium. Human CA10 is 328 amino acids (aa) in length. It possesses one carbonic anhydrase domain that contains a utilized phosphorylation site at Thr299. One potential isoform is reported that shows a 22 aa substitution for aa 277-328. Human and mouse CA10 are identical in amino acid sequence.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.