CaM Kinase I Antibody

Western Blot: CaM Kinase I Antibody [NB600-1163] - Analysis of AtT20 cell extract.

Product Discontinued

CaM Kinase I Antibody Summary

• Immunogen: Synthetic Peptide: A(1) V E G P R W K Q A E D I R D I Y D(18)
• Specificity: Detects CaMKI from rat brain extract.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CAMK1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 2 ug/ml
• Application Notes: WB: Detects an approx. 43 kDa protein representing CaMKI from rat brain extract.

Reactivity Notes

Expected cross-reactivity with Human base on sequence identity.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS with 1 mg/ml BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CaM Kinase I Antibody

• calcium/calmodulin-dependent protein kinase I
• calcium/calmodulin-dependent protein kinase type 1
• CaM kinase I alpha
• CaM Kinase I
• CAMKI
• CaM-KI
• caMKI-alpha
• EC 2.7.11
• EC 2.7.11.17
• MGC120317
• MGC120318

Background

Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CAMK1
• Entrez:
  • 171503(Rat)