CALHM1 Antibody - BSA Free

Western Blot: CALHM1 Antibody [NBP1-77112] - Rat liver tissue lysate at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry-Paraffin: CALHM1 Antibody [NBP1-77112] - Rat liver tissue with CALHM1 antibody at 5 ug/mL.

Immunocytochemistry/Immunofluorescence: CALHM1 Antibody [NBP1-77112] - Immunofluorescence of CALHM1 in Rat Liver cells with CALHM1 antibody at 20 ug/mL.

Immunohistochemistry: CALHM1 Antibody - BSA Free [NBP1-77112] - Immunohistochemistry of CALHM1 in rat liver tissue with CALHM1 antibody at 5 u/mL.

Immunocytochemistry/ Immunofluorescence: CALHM1 Antibody - BSA Free [NBP1-77112] - Immunofluorescence of CALHM1 in Rat Liver cells with CALHM1 antibody at 20 u/mL.

Immunohistochemistry: CALHM1 Antibody - BSA Free [NBP1-77112] - Immunohistochemistry of CALHM1 in rat liver tissue with CALHM1 antibody at 5 u/mL.

Immunocytochemistry/ Immunofluorescence: CALHM1 Antibody - BSA Free [NBP1-77112] - Immunofluorescence of CALHM1 in Rat Liver cells with CALHM1 antibody at 20 u/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CALHM1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CALHM1 Antibody - BSA Free (NBP1-77112) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CALHM1. The immunogen is located within amino acids 60 - 110 of CALHM1. Amino Acid Squence: AEEWKRPLGRRAKDPA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CALHM1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  CALHM1 Peptide (NBP1-77112PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for CALHM1 Antibody - BSA Free

• calcium homeostasis modulator 1
• FAM26Ccalcium homeostasis modulator protein 1
• family with sequence similarity 26, member C
• MGC39514
• MGC39617
• Protein FAM26C

Background

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-beta (Abeta) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Abeta levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CALHM1
• Uniprot:
  • NP_001001412(Human)