Caldesmon/CALD1 Antibody (12B5)

Product Discontinued

Caldesmon/CALD1 Antibody (12B5) Summary

• Immunogen: duck gizzard caldesmon (heavy chain).
• Specificity: This reacts with heavy and light forms of human, duck and chicken caldesmon. It does not cross-react with other proteins.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CALD1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000

Reactivity Notes

Human, Duck, and Chicken.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for Caldesmon/CALD1 Antibody (12B5)

• CAD
• CALD1
• caldesmon 1
• Caldesmon
• CDM
• CDMH-CAD
• HCAD
• LCAD
• L-CAD
• MGC21352
• NAG22

Background

Monoclonal anti-Caldesmon may be used for the study of the involvement of caldesmon in contraction, cell movement, shape change, exocytosis and endocytosis. Caldesmon is an actin interacting and calmodulin binding protein found in smooth muscle and other cell types. Caldesmon occurs in both a high molecular weight (120-150 kDa) and a low molecular weight (61-70 kDa) form, depending on the tissue in which it is located. Caldesmon plays a major role in the regulation of smooth muscle and non-muscle contractile events.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CALD1
• Entrez:
  • 800(Human)