C5L2/GPR77 Antibody (468705) [Alexa Fluor™ Plus 594]

• Reactivity: Mu
• Clone: 468705
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 594

C5L2/GPR77 Antibody (468705) [Alexa Fluor™ Plus 594] Summary

• Specificity: This antibody stains mouse C5L2 transfectants but not irrelevant transfectants.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for C5L2/GPR77 Antibody (468705) [Alexa Fluor™ Plus 594]

• C5a anaphylatoxin chemotactic receptor C5L2
• C5L2
• C5L2G-protein coupled receptor 77
• G protein-coupled receptor 77
• G protein-coupled receptor C5L2
• GPF77
• GPR77

Background

C5L2, also known as GPR77, is a 45 kDa 7TM receptor that binds the complement proteins C3a, C4a, and C5a as well as the acylation stimulating peptide (ASP). C5L2 is expressed on various hematopoietic cells where it promotes complement-mediated inflammation. ASP binding to C5L2 on adipocytes triggers triglyceride synthesis and glucose uptake and inhibits lipolysis. Human C5L2 shares 60% amino acid sequence identity with mouse and rat C5L2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.