C5L2/GPR77 Products

Description

Official Gene Symbol: GPR77 Gen Bank Accession Number: NP_060955 Gene ID: 27202 (human) Gene Map Locus: 19q13.33 (human) C5L2 is 337A.A orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.

Bioinformatics

Entrez	27202 Human
Uniprot	NP_060955.1 Human Q9P296 Human
Product By Gene ID	27202
Alternate Names	C5a anaphylatoxin chemotactic receptor C5L2 C5L2G-protein coupled receptor 77 G protein-coupled receptor 77 G protein-coupled receptor C5L2 GPF77

Research Areas for C5L2/GPR77

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GPCR