C4 binding protein B Antibody (1G9) - Azide and BSA Free

Immunoprecipitation: C4 binding protein B Antibody (1G9) [H00000725-M01] - Analysis of C4BPB transfected lysate using anti-C4BPB monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with C4BPB MaxPab rabbit polyclonal antibody.

Sandwich ELISA: C4 binding protein B Antibody (1G9) [H00000725-M01] - Detection limit for recombinant GST tagged C4BPB is 0.1 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, IP
• Clone: 1G9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

C4 binding protein B Antibody (1G9) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: C4BPB (AAH05378, 1 a.a. ~ 251 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MFFWCACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELKAKLL
• Specificity: C4BPB - complement component 4 binding protein, beta (1G9)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: C4BPB
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoprecipitation
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for C4 binding protein B Antibody (1G9) - Azide and BSA Free

• C4b binding protein, beta chain
• C4b-binding protein beta chain
• C4BP
• complement component 4 binding protein, beta chain
• complement component 4 binding protein, beta
• complement component 4-binding protein, beta

Background

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for C4 binding protein B Antibody (H00000725-M01)(1)

Publication using H00000725-M01

• Wells B, Burgess ST, Nisbet AJ. Characterization of the ovine complement 4 binding protein-beta (C4BPB) chain as a serum biomarker for enhanced diagnosis of sheep scab. Mol Cell Probes. 2013-06-01 [PMID: 23542335]

Bioinformatics

• Gene Symbol: C4BPB
• Entrez:
  • 725(Human)
• Uniprot:
  • AAH05378(Human)