C1q Antibody [HRP]

Product Discontinued

C1q Antibody [HRP] Summary

• Immunogen: Human C1q, purified from plasma
• Specificity: Recognizes human C1q, a sub-component of the C1 complement component.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: C1QA
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:400
• Readout System:
  • NovaLume Plus Chemiluminescent Reagent LUM-555
• Control:

  C1q Overexpression Lysate

Reactivity Notes

Use in Human reported in scientific literature (PMID:33808005).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS and HRP stabilizer
• Preservative: 0.01% Thimerosal
• Concentration: 1.0 mg/ml
• Purity: IgG purified

Alternate Names for C1q Antibody [HRP]

• A chain
• complement component 1, q subcomponent, A chain
• complement component 1, q subcomponent, alpha polypeptide

Background

C1q encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

FAQs for C1q Antibody (NB100-62413). (Showing 1 - 1 of 1 FAQ).

1. I am looking for polyclonal/monoclonal antibodies against canine C1q and complement-related. I was wondering if your prooduct does.
   • Please see the provided link below which will take you to our website and all of our C1Q antibodies that are available. Unfortunately we do not currently have an antibody that has been tested in dog but if that would be something you are interested in doing, I would like to invite you to review our Innovator's rewards program. Should you have any questions or concerns, please do not hesitate to contact me directly. C1Q antibodies: Innovators Rewards Program

Bioinformatics

• Gene Symbol: C1QA