Brg1 Antibody (EPNCIR111A)

Product Discontinued

Brg1 Antibody (EPNCIR111A) Summary

• Immunogen: A synthetic peptide corresponding to residues in mouse BRG1 was used as an immunogen.
• Clonality: Monoclonal
• Host: Rabbit
• Gene: SMARCA4
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100 - 250
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100 - 250
  • Immunoprecipitation 1:10 - 100
  • Western Blot 1:10000-50000
• Application Notes: This product is useful in Western Blot,Immunohistochemistry,Immunocytochemistry,Immunoprecipitation,Immunohistochemistry,

Reactivity Notes

Reacts with: Mouse, Rat, Human

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 49% PBS, 0.05% BSA and 50% Glycerol
• Preservative: 0.01% Sodium Azide
• Purity: Tissue culture supernatant

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for Brg1 Antibody (EPNCIR111A)

• ATP-dependent helicase SMARCA4
• BAF190
• BAF190A
• brahma protein-like 1
• Brg1
• BRG1-associated factor 190A
• BRG1SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 4
• BRM/SWI2-related gene 1
• EC 3.6.1
• EC 3.6.4.-
• FLJ39786
• global transcription activator homologous sequence
• homeotic gene regulator
• hSNF2b
• Mitotic growth and transcription activator
• nuclear protein GRB1
• Protein brahma homolog 1
• Protein BRG-1
• RTPS2
• SMARCA4
• SNF2
• SNF2B
• SNF2-beta
• SNF2L4
• SNF2LB
• SNF2-like 4
• subfamily a, member 4
• sucrose nonfermenting-like 4
• SWI/SNF related, matrix associated, actin dependent regulator of chromatin
• SWI2
• transcription activator BRG1

Background

BRG1 protein (brahma-related gene 1) is a member of the SWI/SNF family that mediates ATP-dependent chromatin remodeling processes. BRG is a central catalytic ATPase of the SWI/SNF chromatin-remodeling complex, where it uses energy derived from ATP hydrolysis to disrupt the chromatin architecture of target promoters. As a major co-regulator of transcription, BRG1 has been implicated in the activation and repression of gene expression through the modulation of chromatin in various tissues and physiological conditions. BRG1 appears to be a critical modulator of transcriptional regulation in cellular processes such as transcriptional regulation, replication, DNA repair and recombination (1, 2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SMARCA4
• Entrez:
  • 6597(Human)
• Uniprot:
  • Q3TKT4(Human)