Brg1 Products

Description

BRG1 is encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Alternatively spliced transcripts have been found for this gene, but their full-length natures have not been determined.

Bioinformatics

Entrez	20586 Mouse 6597 Human
Uniprot	NP_003063 Human P51532 Human
Product By Gene ID	6597
Alternate Names	ATP-dependent helicase SMARCA4 BAF190 BAF190A brahma protein-like 1 BRG1-associated factor 190A BRG1SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 4 BRM/SWI2-related gene 1 EC 3.6.1 EC 3.6.4.- FLJ39786 global transcription activator homologous sequence homeotic gene regulator hSNF2b Mitotic growth and transcription activator nuclear protein GRB1 Protein brahma homolog 1 Protein BRG-1 RTPS2 SNF2 SNF2B SNF2-beta SNF2-BETA SNF2L4 SNF2LB SNF2-like 4 subfamily a, member 4 sucrose nonfermenting-like 4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin SWI2 transcription activator BRG1