Bradykinin RB2/BDKRB2 Antibody (JU39-04)

Western Blot: Bradykinin RB2/BDKRB2 Antibody (JU39-04) [NBP2-75421] - Analysis of BDKRB2 on MCF-7 cell lysate using anti-BDKRB2 antibody at 1/500 dilution.

Flow Cytometry: Bradykinin RB2/BDKRB2 Antibody (JU39-04) [NBP2-75421] - Analysis of SH-SY5Y cells with BDKRB2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Product Discontinued

Bradykinin RB2/BDKRB2 Antibody (JU39-04) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Recombinant protein within Human Bradykinin RB2/BDKRB2 aa 262-391 / 391. (SwissProt: P30411 Human)
• Localization: Cell membrane.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: BDKRB2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:50-1:100
  • Immunoprecipitation 1:10-1:50
  • Western Blot 1:500-1:1000
• Theoretical MW: 80 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Bradykinin RB2/BDKRB2 Antibody (JU39-04)

• B2 bradykinin receptor
• B2R
• BDKRB2
• BK-2 receptor
• BK2
• BK-2
• BKR2
• Bradykinin RB2
• bradykinin receptor B2
• BradykininRB2
• BRB2
• DKFZp686O088

Background

BDKRB2, or Bradykinin Receptor B2, mediates smooth muscle contraction, induces relaxation of arteries, and stimulates diuresis. In addition, bradykinin B2 receptor has been implicated in inflammation and response to pain. This receptor is encoded by a single-copy gene. Two variants are produced by alternate start codons. BDKRB2/Bradykinin B2 receptor expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, kidney, lung, placenta, and thyroid libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BDKRB2