BPNT1 Antibody - BSA Free

Western Blot: BPNT1 Antibody [NBP1-32152] - Sample (30ug whole cell lysate)A:HeLa S3 10% SDS PAGE, antibody diluted at 1:500.

Immunohistochemistry-Paraffin: BPNT1 Antibody [NBP1-32152] - Paraffin-embedded mouse pancreas. BPNT1 antibody [N1C3] dilution: 1:500.

Western Blot: BPNT1 Antibody [NBP1-32152] - Sample (50 ug of whole cell lysate) A: Mouse liver 12% SDS PAGE; antibody diluted at 1:1000.

Immunohistochemistry-Paraffin: BPNT1 Antibody [NBP1-32152] - Paraffin-embedded mouse kidney. BPNT1 antibody [N1C3] dilution: 1:500.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

BPNT1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit BPNT1 Antibody - BSA Free (NBP1-32152) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.
• Predicted Species: Rat (94%), Bovine (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BPNT1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 33 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (83%), Xenopus laevis (84%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for BPNT1 Antibody - BSA Free

• 3'(2'), 5'-bisphosphate nucleotidase 1,3'(2')5'-bisphosphate nucleotidase 1
• Bisphosphate 3'-nucleotidase 1
• BPntase
• EC 3.1.3
• EC 3.1.3.7
• PAP-inositol-1,4-phosphatase
• PIP

Background

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: BPNT1