BMPR-IB/ALK-6 Antibody

Western Blot: BMPR-IB/ALK-6 Antibody [H00000658-B01P] - Analysis of BMPR1B expression in transfected 293T cell line by BMPR1B polyclonal antibody. Lane 1: BMPR1B transfected lysate(55.22 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

BMPR-IB/ALK-6 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: BMPR1B (NP_001194.1, 1 a.a. - 502 a.a.) full-length human protein. MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL
• Specificity: BMPR1B - bone morphogenetic protein receptor, type IB,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: BMPR1B
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BMPR-IB/ALK-6 Antibody

• activin receptor-like kinase 6
• ALK-6
• ALK6CDw293
• BMP type-1B receptor
• BMPR1B
• BMPR-1B
• BMPRIB
• BMPR-IB
• bone morphogenetic protein receptor type-1B
• bone morphogenetic protein receptor, type IB
• CDw293 antigen
• CDw293
• EC 2.7.11
• EC 2.7.11.30
• serine/threonine receptor kinase

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BMPR1B
• Entrez:
  • 658(Human)
• Uniprot:
  • NP_001194.1(Human)