BMP-8b Antibody (6D6)

Product Discontinued

BMP-8b Antibody (6D6) Summary

• Immunogen: BMP8B (NP_001711, 274 a.a. ~ 363 a.a) partial recombinant protein with GST tag.KKSNELPQANRLPGIFDDVHGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMMPDAV
• Specificity: BMP8B - bone morphogenetic protein 8b (osteogenic protein 2) (6D6)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: BMP8B
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In ascites fluid
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BMP-8b Antibody (6D6)

• BMP-8
• BMP-8b
• bone morphogenetic protein 8b
• MGC131757
• OP-3

Background

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for BMP-8b Antibody (H00000656-M01A)(1)

Publication using H00000656-M01A

• Mima K, Fukagawa T, Kurashige J et al. Gene expression of bone morphogenic protein 8B in the primary site, peripheral blood and bone marrow of patients with gastric cancer. Oncol Lett 2013-10-19 [PMID: 24137334]

Bioinformatics

• Gene Symbol: BMP8B
• Entrez:
  • 656(Human)
• Uniprot:
  • NP_001711(Human)