Recombinant Human BMP-5 Protein

Product Discontinued

Recombinant Human BMP-5 Protein Summary

• Description: Recombinant bioactive protein for Human BMP-5
  
  

  Source:E. coli
  Amino Acid Sequence:(P22003)

• Preparation Method: Determined to be >98% pure by SDS-PAGE
• Details of Functionality: The ED50 as determined by the dose-dependent induction of alkaline phosphatase production with ATDC5 chondrogenic cells is typically 0.3-3 ug/ml.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: BMP5
• Purity: >98%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 31 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Sterile filtered and lyophilized with no additives
• Concentration: Lyoph
• Purity: >98%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute to a concentration of 0.1 - 1.0 mg/ml in H2O containing BSA (50 ug BSA per 1 ug of protein). This solution can then be diluted into other aqueous buffers andstored at 4C for 1 week or -20C for long-term storage.

Alternate Names for Recombinant Human BMP-5 Protein

• BMP5
• BMP-5
• bone morphogenetic protein 5
• MGC34244

Background

BMPs (bone morphogenetic proteins) belong to the TGF-Beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Human BMP-5 is a 31 kDa homodimeric protein consisting of two 134 amino acid polypeptide chains.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: BMP5