Recombinant Human BMP-5 Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE, Bioactivity
Concentration
Lyoph

Order Details

Recombinant Human BMP-5 Protein Summary

Description
Recombinant bioactive protein for Human BMP-5

Source:E. coli
Amino Acid Sequence:(P22003)

Preparation
Method
Determined to be >98% pure by SDS-PAGE
Details of Functionality
The ED50 as determined by the dose-dependent induction of alkaline phosphatase production with ATDC5 chondrogenic cells is typically 0.3-3 ug/ml.
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
BMP5
Purity
>95%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Applications/Dilutions

Theoretical MW
31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Sterile filtered and lyophilized with no additives
Concentration
Lyoph
Purity
>95%, by SDS-PAGE
Reconstitution Instructions
Reconstitute to a concentration of 0.1-1.0 mg/ml in H2O containing BSA (50 ug BSA per 1 ug of protein). This solution can then be diluted into other aqueous buffers andstored at 4C for 1 week or -20C for long-term storage.

Alternate Names for Recombinant Human BMP-5 Protein

  • BMP5
  • BMP-5
  • bone morphogenetic protein 5
  • MGC34244

Background

BMPs (bone morphogenetic proteins) belong to the TGF-Beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Human BMP-5 is a 31 kDa homodimeric protein consisting of two 134 amino acid polypeptide chains.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol BMP5
Entrez