BIRC8 Antibody

Images

 
Immunohistochemistry-Paraffin: BIRC8 Antibody [NBP1-03071] - Staining of human small intestine, Peyer's patch. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

BIRC8 Antibody Summary

Immunogen
Synthetic peptide from human BIRC8 / ILP2.
Specificity
synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BIRC8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-2 ug/ml
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BIRC8 Antibody

  • baculoviral IAP repeat containing 8
  • baculoviral IAP repeat-containing 8
  • baculoviral IAP repeat-containing protein 8
  • hILP2
  • IAP-like protein 2
  • ILP-2ILP2
  • Inhibitor of apoptosis-like protein 2
  • Testis-specific inhibitor of apoptosis

Background

Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF8221
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
NB100-56548
Species: Hu
Applications: WB, ICC/IF
NB300-264
Species: Hu, Mu
Applications: WB, IHC-P, IP, PLA
NB100-56074
Species: Hu, Mu, Rt, Ge
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NB100-56118
Species: Hu, Mu, Rt, Ca, Ge
Applications: IHC, IHC-Fr, IHC-P, IP, Flow-IC
MAB829
Species: Hu
Applications: WB, IHC
NBP1-00206
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
NB100-56311
Species: Hu
Applications: WB, ICC/IF, IHC-P
AF8241
Species: Hu, Mu
Applications: IHC
NBP2-34122
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-28566
Species: Hu, Mu, Rt, Bv, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IP
NBP1-76798
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
NBP2-50048
Species: Hu, Mu, Rt, Po, Bv, Ch, Eq
Applications: WB, ICC/IF
NB100-77331
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
NBP1-03071
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P

Publications for BIRC8 Antibody (NBP1-03071) (0)

There are no publications for BIRC8 Antibody (NBP1-03071).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for BIRC8 Antibody (NBP1-03071) (0)

There are no reviews for BIRC8 Antibody (NBP1-03071). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for BIRC8 Antibody (NBP1-03071) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional BIRC8 Products

Bioinformatics Tool for BIRC8 Antibody (NBP1-03071)

Discover related pathways, diseases and genes to BIRC8 Antibody (NBP1-03071). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for BIRC8 Antibody (NBP1-03071)

Discover more about diseases related to BIRC8 Antibody (NBP1-03071).
 

Pathways for BIRC8 Antibody (NBP1-03071)

View related products by pathway.

Research Areas for BIRC8 Antibody (NBP1-03071)

Find related products by research area.

Blogs on BIRC8

There are no specific blogs for BIRC8, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our BIRC8 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol BIRC8
Entrez
Uniprot